What to Know About Protein A Antibody Purification

by | Sep 6, 2022 | Business

Antibodies are important protectors, as they defend people against bacteria and viruses. They are used to produce monoclonal antibodies as well, both for therapeutic purposes and research. You want to work with a company that offers Protein A antibody purification, as well as production and expression. Work with a company that has a manufacturing process that allows them to produce high-quality mAbs with high yields.

Purification and Downstream Processing

If you are interested in protein A antibody purification, you need to find a company that can handle the job. They should have the capability and expertise to perform purification and downstream processing for monoclonal antibodies or recombinant protein products. They will either execute your existing purification process or develop one for your cell culture supernatant and protein. Protein purification is essential for studying proteins, and you need to work with a company that has extensive experience and can do the job for you.

Protein A Antibody Purification

When you need protein A antibody purification, you isolate the antibody from the serum, the ascites fluid, or the culture supernatant of a hybridoma cell line or monoclonal antibody. A company that does this can produce antibodies for you using hybridoma cells and scaling up the clone production. They can do large-scale productions and grow cells in a single-use hollow fiber cartridge. This way, there is a continuous flow of media to transport nutrients over semi-permeable fibers into the environment that surrounds it. They will monitor the environment and make sure that antibody synthesis is able to occur. This is a reliable method, and they can do everything necessary to produce antibodies.

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